Searchable abstracts of presentations at key conferences in endocrinology

ea0022p18 | Adrenal | ECE2010

The aldosterone renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma

Rossi GianPaolo , Barisa Marlena , Desideri GiovanBattista , Letizia Claudio , Maccario Mauro , Morganti Alberto , Palumbo Gaetana , Patalano Anna , Realdi Anna , Roman Elisabetta , Seccia Teresa Maria , Pessina Achille Cesare

The screening for primary aldosteronism (PA) is based on the aldosterone/renin ratio (ARR), which is calculated with the plasma renin activity (PRA) as denominator. A direct measurement of active renin (DRA) is being used as an alternative to PRA, but its diagnostic performance remains uncertain.Aim of the study was to head-to-head compare the ARR based on PRA (ARR-P) to on DRA (ARR-D), at baseline and post-captopril, for identifying aldosterone-producin...